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Practical Issues Concerning the Approval and Use of Biosimilar Drugs for the Treatment of Multiple Sclerosis in Latin America
(Springer, 2019)
The use of biosimilar drugs for multiple sclerosis (MS) has become widespread in Latin America, with the goal of reducing costs of treatments, promoting the sustainability of healthcare systems, and improving patient ...
Pharmacokinetics of combined treatment with praziquantel and albendazole in neurocysticercosis
(Wiley, 2011)
Neurocysticercosis is the most common cause of acquired epilepsy in the world. Antiparasitic treatment of viable brain cysts is of clinical benefit, but current antiparasitic regimes provide incomplete parasiticidal efficacy. ...
Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: A randomized, placebo-controlled first-inhuman single-dose escalation study
(American Society for Microbiology, 2019)
Cysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of ...
Long-Term Efficacy and Safety of Biosimilar CT-P10 Versus Innovator Rituximab in Rheumatoid Arthritis: 48-Week Results from a Randomized Phase III Trial
(Springer, 2019)
Objective: The aim of this study was to investigate long-term clinical outcomes of extended treatment with CT-P10, a rituximab biosimilar, compared with rituximab reference products sourced from the USA and the EU (US-RTX ...
Biological and nonbiological complex drugs for multiple sclerosis in Latin America: Regulations and risk management
(Taylor and Francis, 2015)
Biological drugs and nonbiological complex drugs with expired patents are followed by biosimilars and follow-on drugs that are supposedly similar and comparable with the reference product in terms of quality, safety and ...
Tocilizumab in COVID-19: Enthusiasm vs. evidence
(Wolters Kluwer Health, 2021)
Based on the pathophysiological characterization of COVID-19, initial studies suggested the use of tocilizumab (TCZ), a recombinant humanized monoclonal antibody of the immunoglobulin G1 class, for management of the cytokine ...
Nanostructured voltammetric sensor for ultra-trace anabolic drug determination in food safety field
(2013-11)
A sensitive electrochemical sensor for clenbuterol (CL) determination in bovine urine samples was designed. This drug was originally developed for the treatment of respiratory pathologies. However, in the livestock industry, ...
Potential Medication Incompatibilities In Pediatric Oncology Prescriptions
(HCPA/FAMED/UFRGS, 2023)